Aripiprazole: What Is It? What Is It Used For? Detailed Prospectus

Aripiprazole: What Is It? What Is It Used For? Detailed Prospectus

  • Active Ingredient: Aripiprazole
  • Indications:
    • Antipsychotic: Aripiprazole is an atypical antipsychotic used primarily to treat schizophrenia, bipolar disorder, and major depressive disorder.
    • Schizophrenia: It helps reduce symptoms such as delusions, hallucinations, and disorganized thinking.
    • Bipolar Disorder: Used to treat manic or mixed episodes in bipolar disorder, improving mood stability.
    • Adjunct Therapy for Depression: Often used as an adjunct treatment in major depressive disorder for patients who have not responded well to antidepressants.
  • Dosage Instructions:
    • Adults: The usual dose for schizophrenia and bipolar disorder is 10-15 mg per day. The dose can be adjusted based on the individual’s response to the medication.
    • Children (ages 6-17): Dosage varies depending on the condition being treated, but usually, it starts at lower doses of 2-5 mg per day and is gradually increased.
    • Special Instructions: Aripiprazole should be taken consistently at the same time each day. It can be taken with or without food. Regular follow-ups are required to monitor side effects and effectiveness.
  • Side Effects:
    • Common: Weight gain, dizziness, headache, nausea, insomnia, and anxiety.
    • Severe: Tardive dyskinesia (uncontrolled movements), neuroleptic malignant syndrome (a life-threatening condition), chest pain, difficulty swallowing, or changes in heart rhythm.
    • If any severe symptoms occur, contact your healthcare provider immediately.
  • Warnings:
    • Neuroleptic Malignant Syndrome: A rare but serious condition characterized by fever, muscle rigidity, and altered mental status. Seek immediate medical attention if you experience these symptoms.
    • Tardive Dyskinesia: Long-term use can lead to involuntary muscle movements, especially around the mouth and face. Early detection and discontinuation of the drug may help prevent permanent damage.
    • Suicidal Thoughts: Antipsychotic medications may increase the risk of suicidal thoughts, particularly in young adults and adolescents. Monitor for mood changes, especially during the initial phase of treatment.
    • Pregnancy & Breastfeeding: Use only if the benefits outweigh the risks. Aripiprazole can pass into breast milk, so it is not recommended for breastfeeding mothers without consulting a doctor.
  • Drug Interactions:
    • Antidepressants: Caution when used with SSRIs, SNRIs, or other antidepressants, as the risk of serotonin syndrome (a potentially life-threatening condition) increases.
    • Blood Pressure Medications: Can interact with medications that lower blood pressure, possibly leading to excessive drowsiness or fainting.
    • Alcohol: Avoid drinking alcohol while taking Aripiprazole, as it can increase the risk of side effects, such as dizziness and drowsiness.
  • Storage Instructions:
    • Store at room temperature, away from moisture and heat.
    • Keep the medication in its original container, tightly closed, and out of the reach of children.
  • Expiration Date:

    • Do not use after the expiration date listed on the packaging. Safely dispose of expired or unused medication.

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