Azithromycin: What Is It? What Is It Used For? Detailed Prospectus

Azithromycin: What Is It? What Is It Used For? Detailed Prospectus

  • Active Ingredient: Azithromycin
  • Indications:
    • Antibiotic: Azithromycin is a macrolide antibiotic used to treat a variety of bacterial infections.
    • Respiratory Infections: It is commonly prescribed for respiratory infections such as pneumonia, bronchitis, and sinusitis.
    • Ear Infections: Used for middle ear infections (otitis media), especially in children.
    • Skin Infections: Azithromycin can be used for treating skin infections, including impetigo and cellulitis.
    • Sexually Transmitted Infections: It is sometimes used to treat sexually transmitted infections like chlamydia and gonorrhea.
    • Prevention of Mycobacterium Avium Complex (MAC): Azithromycin is used to prevent infections caused by MAC in patients with HIV.
  • Dosage Instructions:
    • Adults: The usual dose for most infections is 500 mg once daily for 3 to 5 days, depending on the infection.
    • Children: The dose for children is based on their weight and the specific infection being treated. Typically, the dosage is between 10 mg/kg to 20 mg/kg per day, usually for 3 to 5 days.
    • Special Instructions: Azithromycin should be taken at least 1 hour before or 2 hours after a meal. Take the medication at the same time each day. If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose.
  • Side Effects:
    • Common: Diarrhea, nausea, vomiting, stomach pain, and fatigue.
    • Severe: Allergic reactions (swelling, rash, difficulty breathing), liver problems (yellowing of the skin or eyes), severe diarrhea, or heart rhythm changes (QT prolongation).
    • If you experience any severe symptoms, contact your healthcare provider immediately.
  • Warnings:
    • Heart Problems: Azithromycin can cause a rare but serious heart issue called QT prolongation, which can lead to life-threatening arrhythmias (irregular heart rhythms).
    • Liver Health: Caution is required for those with liver disease, as Azithromycin can impact liver function. Regular monitoring is recommended.
    • Pregnancy & Breastfeeding: Azithromycin is classified as Category B for pregnancy, meaning it is generally considered safe but should be used only if clearly needed. It passes into breast milk, so consult your doctor before using it during breastfeeding.
    • Allergic Reactions: If you have a history of allergies to macrolide antibiotics, you should avoid using Azithromycin.
  • Drug Interactions:
    • Antacids: Antacids containing aluminum or magnesium can reduce the absorption of Azithromycin. It’s best to take Azithromycin at least 2 hours before or 4 hours after taking an antacid.
    • Blood Thinners: Caution when taking Azithromycin with anticoagulants (e.g., warfarin), as it may increase the risk of bleeding.
    • Antiarrhythmic Medications: Using Azithromycin with other drugs that affect heart rhythm (e.g., quinidine or amiodarone) may increase the risk of heart issues.
  • Storage Instructions:
    • Store at room temperature, away from moisture and light.
    • Keep the medication in its original container and tightly closed to protect it from light and humidity.
    • Keep out of the reach of children.
  • Expiration Date:

    • Do not use after the expiration date listed on the packaging. Safely dispose of unused or expired medication.

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